Endocrine Abstracts

Introduction: Acromegaly is a disease caused by excessive secretion of growth hormone and subsequently insulin growth factor 1. It is believed that this oversecretion can cause increased prevalence of nodular goiter and thyroid cancer. However, the amount of studies comparing acromegalic patients with control groups is low. The aim of the study was to assess the prevalence of thyroid lesions in patients with acromegaly in comparison with age and sex-matched control group.<...

Introduction: Acromegaly is a relatively rare endocrine condition caused by GH oversecretion by pituitary adenoma. Its most frequent complications include cardiovascular and respiratory system diseases with high tendency of neoplastic transformation and increased risk of benign and malignant tumors. The aim of this retrospective study was to assess the prevalence of benign and malignant neoplasms in patients with acromegaly.Materials and methods: We have...

Thyrotropinoma is a very rare cause of hyperthyroidism. In October 2014 a 41-year-old male patient was examined for anaemia and diarrhoea. Abdomen CT scan, gastroscopy, colonoscopy and parasite tests did not reveal any abnormalities. The patient had lost 18 kg 7 years ago and his weight had been stable since then (BMI 21.3 kg/m2). The laboratory tests revealed high TSH, normal fT4 and low cortisol level. The patient referred to our department presented wi...

Introduction: Elastography is a method of tissue stiffness assessment. It was already demonstrated that thyroid cancers are less elastic than benign lesions. However, little is known about other factors, which might influence the stiffness of thyroid nodules and disrupt the prediction of malignancy using this technique. The aim of this study was to conduct the first systematic assessment of factors potentially affecting elasticity of thyroid lesions.Meth...

Introduction: According to a high prevalence and relatively low occurrence of malignancies in thyroid nodular disease (TND), the selection of suspicious lesions for fine – needle aspiration biopsy (FNAB) seem to be a vital problem in the daily endocrinological practice. Beside deciding if the FNAB is necessary, frequently the second problem occurs – which nodule or nodules should be chosen in case of multinodular goiter (MNG), when the number of potential lesions for...